Question

choices for A: hemidesmosomes, focal contacts, desmosomes, adherens junctions

choices for B: integrin, cadherin, occludin

choices for C: intermediate filaments, microtubles, the actin cytoskeleton

choices for D: focal contacts, desmosomes, edherens junctions, hemidesmosomes

choices for E: integrin, cadherin, occludin

choices for F: microtubles, intermediate filaments, the actin cytoskeleton

Animal cells use a wide variety of junctions to connect cells to each other and to their ECM. The function of these junctions are determined by the proteins involved. Motile cells can interact dynamically with the ECM via [Select] which require the transmembrane protein (Select] and connects the ECM to [Select) via linker proteins. In contrast, epithelial cells form stable interactions with the basil lamina via (Select] which require the transmembrane protein [Select) and connects the ECM to [Select] via linker proteins.

Answer 1

The right choices are as follow:

(A) focal contact

(B) integrin

(C) the actin cytoskeleton

(D) adherence junction

(E) cadherin

(F) the actin cytoskeleton

Explanation:

Focal adhesion (focal contact): It is a type of adhesive contact in which the cell and ECM interact through the transmembrane proteins integrins with their extracellular ligands, and intracellular multiprotein assemblies connected to the actin cytoskeleton.

The integrins are the major trans-membrane receptors that facilitate dynamic interactions between the ECM and the actin cytoskeleton for cell motility.

Adherence junction: It provide stable interaction between ECM and epithellial cell in which the cytosolic adaptor proteins complex facilitate the connection between cadherins and actin cytoskeleton.