Question

Can someone explain to me why the answer is 1/24? thanks

In the following pedigree Individuals III- 3 and III-4 married without knowing they were related. They are expecting and they ask you to estimate the probability that the child will have the condition. OT ? A. 1/64 B. 1/24 C. 1/48 D. 1/4 E. Another fraction The following nodigree correcnonds to a family where come

Answer 1

In the following pedigree individual 14 is affected. His mother and father both are normal. so, the trait is a recessive trait. It is not x-linked because the mother has another son who is unaffected. So, the pedigree is recessive. Individual 14 have both normal parents. So, his parents are heterozy gous. Aa X Aa autosomal А А AA Aa Aa acit affected a heterozygous Chance of H-4 so, the chance of individual Is is is 3 to be a carries is, 3x £ z 3 chance of 1-4 transmitt the recessive allele to his offspring = + x 2 = 16

Individual I-2 to being a carrier z 1 Because her mother is heterozygous for the trait. chance of II-2 , to transmit her recessive allele to D-3 is, ㅗ Chance of 1-3 trans mit her recessive allele to her offspring + x 2 = 16 so, the to the child of 11-3 and m-4 have probability getting the condition ext t the ,و - The answer is the not 1/24