Question

1a. When pKa values are given for amines, which bond (left arrow or the right arrow) is being referenced? H 1b. Fill in the pka values for each bond. N." Note: the term pka = -log (Ka); Ka is the equilibrium when you start with an н. H acid and end with the conj. base. N...MITH H H 2. Is the following molecule chiral at room temperature? Is it chiral at 0 K (abs. zero)? Explain. IIBE H2C1 *CF3 3. Why does mixing ammonia (NH3) with an alkyl halide (excess) lead to a “exhaustive alkylation"? 4. In the Azide Synthesis Mechanism, what make the reaction irreversible?