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2. Explore the 30 anatomical viewin Module 3.4 Milotic Spindle and answer the following questions 3. Examine the illustration

2a. The mitotic spindle is composed of a network of which cytoskeletal filaments?

2b. Some type of chemotherapeutic drugs, used to treat cancer, disrupt microtubules and the mitotic spindle. Why are drugs that disrupt the mitotic spindle effective cancer treatment?

2c. In humans, both meiosis and mitosis start with a cell that has ____ duplicated chromosomes. Remember, cells duplicate their DNA during S phase in the cell cycle; this happens prior to meiosis or mitosis. Meiosis includes two rounds of cell division, whereas mitosis only has one. As a result, cells that arise from meiosis have ____ chromosomes and cells the arise from mitosis have ____ chromosomes.

2d. What is the difference between a diploid cell and haploid cell?
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2a . Mitotic spindle is composed of microtubules. In the beginning of mitosis microtubules combines to form mitotic spindle.

2b. Cancer is the uncontrollable cell proliferation. To control this, microtubule disruption drugs are used. Since mitosis cannot be completed without mitotic spindle ,these drugs can slow down the process of cell division. The drugs bind with microtubules nd disrupt mitotic spindle formtion thus leading to cell death or apoptosis. This will help in controlling cancer.

2c. In humans both meiosis and mitosis starts with cell that has two duplicated chromosomes Or diploid set of chromosomes. Remember,. Cells duplicate their DNA during S phase in cell cycle. This happens prior to meiosis and mitosis.meiosis has two rounds of cell division whereas mitosis has only one. As a result cells arising from meiosis have haploid chromosomes and cells that arise feom mitosis have diploid chromosomes.

2d. The term ploidy refers to the number of chromosome set present in a cell. In diploid cells, two sets of chromosomes can be seen whereas in haploid cells only one set of chromosome is present. Polyploidy refers to more than two set of chromosomes in a single cell.

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