Which of the following would cause an increase in the conversion of IMP to GMP?
|
a. |
high levels of CMP |
|
b. |
high levels of dTTP |
|
c. |
high levels of UMP |
|
d. |
high levels of AMP |
|
e. |
none of the above |
High levels of AMP are going to act as negative feedback system for the production of ATP from IMP and hence in turn will cause increase of conversion of GTP through GMP from IMP. This can be understood by the following example:
There are two roads B and C bifurcating from a single road A and leads to a common path..
Consider B as GMP and C as AMP
Now, flow of traffic at road B is going to increase only in two cases, 1.) if the traffic load at A is less…and 2.) if the traffic load at B is increased.
(In another feed-back system GMP and AMP both decrease the formation of their immediate precursors from IMP; and this type of inhibition is competitive).
Which of the following would cause an increase in the conversion of IMP to GMP? a....
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