Question

Please choose the answer below that best explains why a new class of drug treatment termed "highly active anti-retroviral therapy (HAART) is showing a novel anti-retroviral treatment. Multiple Choice HIV virus production is interrupted at two or more levels which may include retroviral DNA production, viral assembly, prevention of viral DNA integration into the host genome, and others HAART drug treatment decreases viral loads to undetectable levels and results in improvements in the patient's immune functions. Use of HAART drugs reduced the incidence of viral drug resistance All of these choices are correct Dros 2 of 25 Nav!

Answer 1

ANSWER : The new class of drug treatment termed as Highly active anti-retroviral therapy (HAART) is showing a novel anti-retroviral treatment -  All of these choices are correct.

REASON- HAART or Highly active anti-retroviral therapy is a newly modified treatment regimen consisting of a combination of three or even more anti-retroviral drugs.

HIV virus production is interrupted at two or more levels which may include retroviral DNA production ,viral assembly,prevention of viral DNA integration into host genome and others- HAART aims to co-administer various combination of anti-retroviral drugs that inhibits viral replication by various mechanisms- Virus have to cross the host cell membrane at least twice during replication , thus interrupting the viral release and entry by alteration in membrane lipid composition is one of the methods. The drugs can target the specific viral enzymes required for DNA replication and production.The antiviral drug may also target the reverse-transcriptase to prevent DNA integration inti host genome.

HAART drug treatment thus reduces viral loads to undetectable levels and results in improvement in patients immune response- It has shown to reduce plasma viral RNA load by effectively suppressing the viral replication i.e HIV replication and thus keep the immune system healthy which aid in better immune response.

Use of HAART drugs reduced the incidence of viral drug resistance- The combination anti-retroviral therapy (ART) also known as highly active anti-retroviral therapy (HAART ) is shown to use a combination strategy of anti-viral drugs that is successful in reducing the incidence of viral drug resistance.