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What is Knudson’s Two hit hypothesis? And what is the general message?

What is Knudson’s Two hit hypothesis? And what is the general message?
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mud Hplet hypothe , is that tue caueer is tue re accumiudalkd mutahtou to a cels ONA. Knud sou suges tat mulhple tis o DNA were neessa to Cauve canes Suppresor genes A muao otti e atteics s vequired ,as

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What is Knudson’s Two hit hypothesis? And what is the general message?
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