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20. In which of the following configurations is the myosin filament in a high energy state?...

20. In which of the following configurations is the myosin filament in a high energy state?

a. when the myosin fibril is bound to ATP

b. when the myosin filament is bound to ADP and inorganic phosphate

c. when the myosin filament is bound to the actin filament immediately after the power stroke

d. when the head of the myosin filament is not bound to anything

e. none of the above

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Answer #1

When ATP binds to myosin, actin gets detached from myosin. The ATP is then converted to ADP and inorganic phosphate by ATPase. ATP hydrolysis generates energy and the released energy changes the myosin head angle into a “cocked” position. Myosin in the form of myosin ADP-Pi complex and in a cocked position is now in a high energy state. So, the correct option is option B, When the myosin filament is bound to ADP and inorganic phosphate.

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