Recently, in a daring yet terrifying act of a totalitarian, North Korea's dictator Kim Jung Un had his half-brother murdered in the Malaysian airport by agents who deployed VX poison. VX poison is a potent acetylcholinesterase inhibitor. What effect does VX have on muscle funtion? Fill in the blanks in the explanation below. A word bank of choices follows. Because the removal of acetylcholine is inhibited, the muscle membrane at the nueromuscular junction will remain depolarized for an abnormally long period, causing the muscles to remain in a state. The prolonged in turn would be propagated via the T tubule system to . The result would be prolonged release of calcium, resulting in sarcomere via the effects of calcium on . Selections: polarized; depolarized; polarization; depolarization; shortening; relaxing; contracted; the sarcoplasmic reticulum; the troponin system; myosin; Z lines
Because the removal of acetylcholine is inhibited, the muscle membrane at the neuromuscular junction will remain depolarised for an abnormally long period, causing the muscle to remain in a depolarised state. Te depolarisation in turn in turn would be propagated via the T tubule system to sacroplasmic reticulum. The result would be prolonged release of calcium, resulting in sarcomere shortening via the effects of calcium ion.
Recently, in a daring yet terrifying act of a totalitarian, North Korea's dictator Kim Jung Un...