1.True-
Dystrophin is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane .
Muscular dystrophy is caused by genetic mutations that interfere with the production of muscle proteins that are needed to build and maintain healthy muscles. It is caused by mutations in the DMD gene, resulting in deficiency or absence of functional dystrophin
2.Perlecan
Perlecan is a large multidomain proteoglycan that binds to and cross-links many extracellular matrix (ECM) components and cell-surface molecules.
All others Laminin,collagen,Integrin are ECM proteins.
Connections between the ECM and cytoskeleton, specifically the dystrophin- glycoprotein, are defective in muscular dystrophy. True...
4) In migrating cells, ______ are stable links between the ECM and the actin cytoskeleton 5) Which one of the following is true? All integrin-containing adhesion complexes have the same cytoplasmic components the spatial organization of integrin-containing adhesion complexes varies depending on the nature of ECM contacting the cell integrin-containing adhesion complexes connect microtubules to the ECM integrin activation involves conformational changes of the extracellular but not intracellular domains of integrins What protective function does calcium gating serve in gap...
Dystrophin is a protein that forms part of a vital protein complex that connects the cytoskeleton of a muscle fiber cell to the extracellular matrix. This connection strengthens and shapes the muscle fibers. Dystrophin is coded by the DMD gene. This is one of the longest human genes known, covering 2,300,000 base pairs (0.08% of the human genome) It is located in chromosome 21. The immature mRNA is 2,100,000 bases long and takes 16 hours to transcribe. It contains 79...
Question 78 Which of the following statements about the cytoskeleton is TRUE? All eukaryotic cells have actin, microtubules, and intermediate filaments in their cytoplasm The cytoskeleton provides a rigid and unchangeable structure important for the shape of the cell. The three cytoskeletal filaments perform distinct tasks in the cell and act completely independently of one another Actin filaments and microtubules have an inherent polarity, with a plus end that grows more quickly than the minus end С. D Question 79...
Which of the following is carried out by enzymes in the cytosol Select one: a. oxidative phosphorylation b. the Krebs cycle c. chemiosmotic coupling d. glycolysis Which best describes the extracellular matrix? Select one: a. It surrounds cells; it contains proteins, polysaccharides, and minerals; it provides a scaffold for cell attachment; and it transmits chemical messengers to cells. b. It is found just inside the cell membrane in all tissues, it sends branching collagen fibers between cells to connect them,...
Question 15: Which of the following statements is false? A. Mitotic Cdk must be phosphorylated by an activating kinase (Cak) before it is active. B. Phosphorylation of mitotic Cdk by the inhibitory kinase (Wee1) makes the Cdk inactive, even if it is phosphorylated by the activating kinase. C. Active M-Cdk phosphorylates the activating phosphatase (Cdc25) in a positive feedback loop. D. The activating phosphatase (Cdc25) removes all phosphates from mitotic Cdk so that M-Cdk will be active. Question 18: Which...
1) Discuss the importance of magnification and resolution in microscopy. How are the magnification and resolution of a light microscope different from that of an electron microscope? 2) Which microscope would you use to study the following? a) the changes in shape of a living human white blood cell b) the finest details of the surface texture of a human hair c) the detailed structure of an organelle in a liver cell 3) State the cell theory?...
linear algebra question easy, please answer fast with steps
Mark each statement True or False. Justify each answer. Here A is an mxn matrix. Complete parts (a) through (e) below a. If B is a basis for a subspace H, then each vector in H can be wrben in only one way as a linear combination of the vectors in B. Choose the correct answer below O A. The statement is false. Bases for a subspace H may be linear...
1. Like phospholipids, lipopolysaccharides have a hydrophilic head and a hydrophobic tail. True or false 2. The outer membrane of Gram negative bacteria contains lipopolysaccharides T or F 3. Biofilms and pure culture are formed by only one type of microorganism T or F 4. Any given antibiotic will have the same minimum inhibitory concentration (MIC) against any test microorganism. T or F 5. Production of antibiotics by the microorganism is not affected by the culture conditions T or F...
QUESTION 1 Human microbiota resides in the a. intestines. b. kidneys. c. liver. d. cerebral spinal fluid. 5 points QUESTION 2 The entry, establishment, and multiplication of a pathogen is a. inflammation. b. a disease. c. infection. d. exposure. 5 points QUESTION 3 Indirect methods of disease transmission include a. sneezing. b. eating contaminated food. c. coughing. d. shaking hands. 5 points QUESTION 4 For an infection to be established, the host must a. create a portal...
human disease
Vitamins Minerals are a sential substances that Our whes nees to seelun Ons tunc on norm List 2 examples of Vitamins/Minerals: maly. Muscle Relaxants: List 3 examples of Muscle Relaxants: Anatomy, Physiology, and Disease Exercises and Homework - Muscular Skeletal System (Module 2) True or False- 1. Bones are very vascular, allowing for blood to circulate through them 2. Cartilage provides protection and a cushion to prevent friction between bones 3. One of the functions of muscles is...