Which of the following modifications would make the resting potential of the neuron more positive? (select...
Which of the following modifications would make the resting potential of the neuron more positive? (select all that apply)
Increase the extracellular Ca2+ concentration
Increase the intracellular Ca2+ concentration
Increase the extracellular Cl- concentration
Increase the intracellular Cl- concentration
Homework Answers
Answer : increase the intracellular Cl-concentration.
Explanation : During the resting membrane potential, there is a difference between the charge present across the membrane. The outside of the cell is more positively charged while the intracellular space or inside environment of cell is negatively charged. During resting membrane potential the charge difference across the membrane remains nearly equal to -70 mV. So, if we will increase the intracellular Cl- concentration, than the potential difference across the membrane will be decreased and the potential difference will become more positive.
During resting membrane potential, the concentration of Sodium and Calcium ions are more in the extracellular fluid and the concentration of Potassium and chlorine ions are more in the intracellular fluid.
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Which of the following modifications would make the resting
potential of the neuron more positive? (select...
D 4. Which of the following is TRUE regarding the resting state of a neuron? There...
D 4. Which of the following is TRUE regarding the resting state of a neuron? There is more K+ outside of the neuron than there is inside of the neuron. During the resting state, all of the Na+ and K+ leaky channels are nonfunctional The H+-ATPase pump is responsible for establishing the resting electrochemical gradient in the neuron. The outside of the neural cell has a positive charge while the inside of the neural cell has a negative charge.
Scenario: You will participate in a research project that involves working with neurons that are kept...
Scenario: You will participate in a research project
that involves working with neurons that are kept in cell culture.
These neurons are well established cell model and their
intracellular and extracellular environments are known. Required
parameters are listed in the table below. All your experiments will
be carried out at 20 ?C.
Calculate equilibrium potentials E for all ion species
listed in the table below, as well as the resulting membrane
resting potential VM.
But some calculations first! Intracellular Concentration...
Question 8 1 pts In living cells, which of the following manipulations would cause the resting...
Question 8 1 pts In living cells, which of the following manipulations would cause the resting membrane potential (i.e. Erest) of a living neuron to become more electronegative? Decreasing the threshold of a neuron Increasing the number of opened K+ leak channels in the plasma membrane Decreasing the ICF/cytoplasmic K* concentration Decreasing the number of voltage-gated Nat channels Decreasing the activity of the Nat/K* ATPase
QUESTION 8 he membrane potential becomes more negative than the resting potential during the after-hyperpolarization phase...
QUESTION 8 he membrane potential becomes more negative than the resting potential during the after-hyperpolarization phase of the action potential (AHP) because Ligand-galed Nat channels are inactivated and cannot be opened Voltage-gated K channels become inactivated The K equilibrium potential is below the resting membrane potential All ofthe above. None of the above QUESTION 9 When an action potential reaches the axon terminal, release of neurotransmitter is triggered by... a. movement of sodium ions into the axon terminal b. movement...
With respect to the membrane potential which of the following is NOT true? A. In resting...
With respect to the membrane potential which of the following is NOT true? A. In resting cells, the membrane potential is negative because sodium ions are less permeable than potassium ions. B. The resting potential of the nerve cell depends on voltage gated potassium channels C. While chloride is much more permeable than sodium, it adds relatively little to the negative membrane potential. D. The concentration of chloride inside/outside the cell is the reciprocal of the potassium concentration of the...
A cell has a resting membrane potential of -70mV. In each of the following cases, would...
A cell has a resting membrane potential of -70mV. In each of the following cases, would the cell depolarize, or hyperpolarize? Justify your answers with a written explanation that relates to the GHK equation; you do not need to calculate new membrane potentials, but you should explain why the changes would occur. Hint: Use the simulations from class to solve these Cell becomes more permeable to Cl- Cell becomes more permeable to Ca++ (Hint: which ion shown in the simulation...
Which of the following would be an effect of consuming caffeine in your morning coffee? [Select...
Which of the following would be an effect of consuming caffeine in your morning coffee? [Select all that apply] A. Adenosine cannot bind its receptor B. Adenosine cannot induce its inhibitory effects on the post-synaptic neuron C. Excitatory effects on the post-synaptic neuron, due to the lack of inhibitory effect of adenosine on the post-synaptic neuron D. More action potentials on the post-synaptic neuron, leading to increased alertness
Order the following events that occur in a neuron in response to a stimulus Sodium Potassium...
Order the following events that occur in a neuron in response
to a stimulus
Sodium Potassium Pumps and Potassium Leak Channels re-establish the resting potential Voltage Gated Potassium channels close The inside of the cell becomes more negative than the original resting potential V Voltage Gated Sodium channels open Sodium ions rush into the cell The inside of the cell becomes temporarily positive Votage Cated Potatalum channels open which causes potassium to flood out of the cell
You are recording from the postsynaptic neuron at a glutamatergic synapse that contains AMPA and NMDA...
You are recording from the postsynaptic neuron at a
glutamatergic synapse that contains AMPA and NMDA receptors. You
stimulate the presynaptic neuron and record an EPSP. You then apply
ketamine to the synapse and allow enough time for it to have its
effect on the synapse (several minutes). Then you stimulate the
presynaptic neuron again and record the resulting EPSP. Which of
the following sets of plots indicates what your results would look
like? ***Note that the y-axes on the...
1) In a regular neuron, the Nernst potential of K+ is about -90 mV. If a...
1) In a regular neuron, the Nernst potential of K+ is about -90 mV. If a scientist utilizes a drug that adheres to and blocks 50% of K+ leak channels, what will the new Nernst potential of K+ be? 0 mV -45 mV -90 mV -135 mV -180 mV 2) If the number of ion channels in the membrane is decreased, which of the following would happen? Select all choices that would apply The length constant increases. The length constant...
D 4. Which of the following is TRUE regarding the resting state of a neuron? There is more K+ outside of the neuron than there is inside of the neuron. During the resting state, all of the Na+ and K+ leaky channels are nonfunctional The H+-ATPase pump is responsible for establishing the resting electrochemical gradient in the neuron. The outside of the neural cell has a positive charge while the inside of the neural cell has a negative charge.
Scenario: You will participate in a research project
that involves working with neurons that are kept in cell culture.
These neurons are well established cell model and their
intracellular and extracellular environments are known. Required
parameters are listed in the table below. All your experiments will
be carried out at 20 ?C.
Calculate equilibrium potentials E for all ion species
listed in the table below, as well as the resulting membrane
resting potential VM.
But some calculations first! Intracellular Concentration...
Question 8 1 pts In living cells, which of the following manipulations would cause the resting membrane potential (i.e. Erest) of a living neuron to become more electronegative? Decreasing the threshold of a neuron Increasing the number of opened K+ leak channels in the plasma membrane Decreasing the ICF/cytoplasmic K* concentration Decreasing the number of voltage-gated Nat channels Decreasing the activity of the Nat/K* ATPase
QUESTION 8 he membrane potential becomes more negative than the resting potential during the after-hyperpolarization phase of the action potential (AHP) because Ligand-galed Nat channels are inactivated and cannot be opened Voltage-gated K channels become inactivated The K equilibrium potential is below the resting membrane potential All ofthe above. None of the above QUESTION 9 When an action potential reaches the axon terminal, release of neurotransmitter is triggered by... a. movement of sodium ions into the axon terminal b. movement...
Order the following events that occur in a neuron in response
to a stimulus
Sodium Potassium Pumps and Potassium Leak Channels re-establish the resting potential Voltage Gated Potassium channels close The inside of the cell becomes more negative than the original resting potential V Voltage Gated Sodium channels open Sodium ions rush into the cell The inside of the cell becomes temporarily positive Votage Cated Potatalum channels open which causes potassium to flood out of the cell
You are recording from the postsynaptic neuron at a
glutamatergic synapse that contains AMPA and NMDA receptors. You
stimulate the presynaptic neuron and record an EPSP. You then apply
ketamine to the synapse and allow enough time for it to have its
effect on the synapse (several minutes). Then you stimulate the
presynaptic neuron again and record the resulting EPSP. Which of
the following sets of plots indicates what your results would look
like? ***Note that the y-axes on the...
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