Question

Create a table and label the left column, “SN2” and the right column, “SN1”. Provide 5 factors that affect nucleophilic substitution reactions. Provide a specific example for each and thoroughly explain each factor.

Answer 1

SN2 SNL of SNL Factors effect the reach ① Nature of the with inereasing storie with in eneasing store's substrate crowding rate of sN2 rati erowding decrease . increase CHg 1 > > > > > I > CH₂ I 1 Nature of solvent Generally no effect more the polas is solvent but depends on the more will be easbocation nature of substrate stable, so increase rate of reach H2O) H₂S JETOH nueliophile nu does ① Nature of attacking attacking should be more nucleophile. not involve in rds nucho philie than this has no effect leaving gr. ② Nature of leaving Highus the leaving Has effect. Sineerds nature of leaving gr. does nombor involve the leaving gr. Highes the leaving nature nights is the rate forreleure with increasing common eg- Rze-el in nael. throth & the As attacking group Highes is the rate TOX Bro y con to ore effect Common ion effect CH3 rds OH rds JOH