Question

Prenatal injection of the sow (mature female hog) during gestation with recombinant porcine somatotropin (rpST) will increase muscle growth potential of her progeny, and intramuscular rpST injections of market hogs will also stimulate muscle growth.

**What mechanism explains muscle hypertrophy in each scenario, and which effect is longer lasting?**

HINT: Prenatal injection with rpST will alter hyperplasia of muscle progenitor cells.

NO COPYING AND PASTING PLEASE

Answer 1

Porcine somatotropin (PST) is a single polypeptide having around 190 different amino acids. They exist in 3 different forms Reporcine rightarrow methionine attached to N-terminal of amino acid chain. Gholene rightarrow In this from N-terminal end first 7 amino acids are removed Somagrepor rightarrow They have extra 3 amino acids attached to N terminal. With help on recombinant DNA technology a new form called recombinant porcine somatotropin (rPST) is being developed that changes the metabolism of connective bene tissues, liver, skeletal muscles, kidney etc. The intramuscular rPST will show long lasting muscle Hypertrophy because as soon as the rPST enter the blood stream it caused the size of cells to increase, as the size increase so do the muscles increase. Whereas prenatal injection with rPST will alter hyperplasia of muscle progenitor cells that results in short muscle hypertrophy only skeletal muscles or cardiac muscles can undergo hypertrophy so the above case is possible as