You and your spouse are considering starting a family, but you just learned that your spouse’s...
You and your spouse are considering starting a family, but you just learned that your spouse’s brother has hemochromatosis. Your spouse and your parents-in-law do not have the disease. What are the chances that your child will have hemochromatosis? Draw a pedigree showing you (i) as a female and (ii) as a male. Both you and your spouse have three siblings each. Show outcomes for your four offspring.
Homework Answers
A gene called HFE is often cause heriditary hemochromatosis.
If my spose inherit one gene each from her parents, the HFE gene have two common mutations, C282Y and H63D.
If our child inherited two abnormal genes, he may develop hemo chromatosis. and they will pass that mutation to thier next generation.
If our child inherited with one abnormal gene, they wont develop hemo chromatosis. they will act as a carrier to pass the mutation to the next generation. they wont develop hemochromatosis until they get inherited with another abnormal gene from the other parents.
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You and your spouse are considering starting a family, but you
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Information Flag question Information text You are consulting with a family where sometimes a mutation that...
Information
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Information text
You are consulting with a family where sometimes a mutation that
leads to deafness (D) and a mutation that predisposes
individuals to early heart failure (H) are
linked. Normally these two traits sort independently
but, in some individuals, a reciprocal translocation has moved them
to the same chromosome. The chromosome maps for an individual with
two normal chromosome pairs (Normal Arrangement), and a
translocation heterozygote (Translocation Arrangement) are shown
below.
Deafness and early heart failure are...
Mike and Mary are planning a family. In addition to their love for each other and...
Mike and Mary are planning a family. In addition to their love for each other and for Game of Thrones, they have something else in common. They each have a history of cystic fibrosis in their family. Cystic fibrosis (CF) is an autosomal recessive disease. i. Mary does not have CF, two of her three sisters have CF, and her mother didn’t have it. But her father did. ii. Mike does not have CF, and two of his three brothers...
A family tree of sorts is called a pedigree. The symbols used for a pedigree are: O female, unaffected Siblings are placed in birth order from left to right and are labeled with Arabic numerals. Each generation is labeled with a Roman numeral. Therefore the male exhbiting the female, affected male, unaffected trait in the pedigree below in the bottom, center would be identified as Il-4. male, affected -utington's Disease REVIEW – Reading a pedigree and dominant/recessive Inheritance. For questions...
Styles 6. Insert a picture of your pedigree chart for this family with genotypes filled in here. 7. Which pattern of inheritance do you think the disease shows? Explain your reasoning. 8. Patient 1 and Patient 2 in the pedigree chart would like to know what the chances are that they will have a child with the disease. What do you tell them? Use a Punnett Square to show your work. Using Punnett Squares for human conditions and diseases The...
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Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with a new disease caused by a mutant gene has been found. The family history has been collected and recorded. You will now create a pedigree chart from their family history and use the pedigree to predict the pattern of inheritance the disease follows. • Read the following family history: Patient 1 and Patient 2 visited a genetics counselor and provided their family histories. As...
Follow-Up Questions 1. Your brother has an autosomal recessive disorder, while you are unaffected. Neither one of your parents is affected. Explain how this is possible. 2. Using the above situation, what is the probability that you carry the recessive allele? 3. A couple wants to have a child, but the mother has a brother who is affected by cystic fibrosis. They seek out the advice of a genetic counselor at their local hospital to determine what, if any, chance...
Information
Flag question
Information text
You are consulting with a family where sometimes a mutation that
leads to deafness (D) and a mutation that predisposes
individuals to early heart failure (H) are
linked. Normally these two traits sort independently
but, in some individuals, a reciprocal translocation has moved them
to the same chromosome. The chromosome maps for an individual with
two normal chromosome pairs (Normal Arrangement), and a
translocation heterozygote (Translocation Arrangement) are shown
below.
Deafness and early heart failure are...
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