Question

(C) You want to determine if there are additional genes associated with deatness. You have more rabbits who are true breeding for deafness (the rabbit lines labeled D3-Db the table below). You mate them with deaf individuals that are homozygous for the recessive alleles of genes aa (rabbit line D1) and bb (rabbit line D2) to perform a complementation test. The phenotypes of the progeny from this complementation les are shown in the table below. Cross Unknown deaf Known deaf rabbit rabbit | D1 (aaBB) Rabbit D3 Offspring are deaf Rabbit D4 Offspring can hear Rabbit D5 Offspring can hear Rabbit D6 Offspring can hear WN - #0 Known deaf rabbit D2 (AAbb) Offspring can hear Offspring are deaf Offspring can hear Offspring can hear 4 L What conclusions can you draw about the genetics of deafness from this experiment? What are the genotypes of rabbits D3 through Do? What experiment might you do next to continue this genetic analysis?

Answer 1

c. After cross it offspring can hear it means that gene. is complementing to deafnes so let's determine the genotype 1. Rabbit D3 – 56-A A-1 da BB * Rabbit D4 aa-l B-B² / A Áb6" Rabit D5 AA-66 |ão - BB 7 knockout for A & Rabbit D6 – #A-66-la a BB , B gene. It shows that two genes are required for hearing. To continue this genetic analysis we can perform a Gross between 03 x 24 and Expect ocutio me will be offsprings can hear beacuse alleles present in D3 & D4 will complement each other.