Question

for the three pathways for complement activation (alternative, lectin, and classical), which pathway is the least efficient at clearing invading bacteria?

for C3 cleavage and amplification cascade, what goes in and what comes out?

Answer 1

Ang lectin pathway is least efficient at clearing invading bacteria. and qt is activated by terminal mannose whesidue of glyw protein or polysaccharide found on surface of bacteria As this bathway does not depend on Ab for activation AS this pathway is activated in the absence of antibody So it baout of innate immune defenses so least efficient in clearing bathogen for Cz cleavage and amplification C convertase is Hequired. C3 Convertase is formed in every pathway via different way but in all c3 convertase Cleave it C2 into two fragment the smaller C39 and larger tuagment C36. C36 now cleave C5, and form c5 convert ase