Question

Can someone please write a route of enzymes and substrates to go from palmitate back to palmitate?

Answer 1

Answer .

Fatty acid synthesis isn't just an inversion of the degradative pathway. Or maybe, it comprises of another arrangement of responses, again embodying the rule that engineered and degradative pathways are quite often particular. Some critical contrasts between the pathways are:

1.

Synthesis happens in the cytosol, conversely with degradation, which happens fundamentally in the mitochondrial grid.

2.

Intermediates in fatty acid synthesis are covalently connected to the sulfhydryl gatherings of an acyl bearer protein (ACP), though intermediates in fatty acid breakdown are covalently appended to the sulfhydryl gathering of coenzyme A.

3.

The enzymes of fatty acid synthesis in higher life forms are participated in a solitary polypeptide chain called fatty acid synthase. Conversely, the degradative enzymes don't appear to be related.

4.

The developing fatty acid chain is stretched by the consecutive expansion of two-carbon units got from acetyl CoA. The actuated benefactor of twocarbon units in the elongation step is malonyl ACP. The elongation response is driven by the arrival of CO2.

5.

The reductant in fatty acid synthesis is NADPH, while the oxidants in fatty acid degradation are NAD+ and FAD.

6.

Elongation by the fatty acid synthase complex stops on arrangement of palmitate (C16). Advance elongation and the addition of double bonds are done by other chemical systems.