Indicate whether each of the following, when active, tends to activate (A) or inactivate (I) M-Cdks. The correct answer will be a four-letter string composed of letters A and I only, e.g. IIAI.
( ) M-Cdk
( ) Cdc20–APC/C
( ) Cdh1–APC/C
( ) Wee1
1 IAIA
2 AIII
3 AIIA
4 IIIA
5 AAII
answer would be
2 AIII
EXPLINATION ...
M-cdks activate other cdks involved in mitosis, Cdc20–APC/C destroys S&M phase cyclins is a part of anaphase promoting complex, Cdh1–APC/C helps in ubiquitination of cyclins and is a part of anaphase promoting complex. Wee1 does inhibitory phosphorylation on cdc2.
Indicate whether each of the following, when active, tends to activate (A) or inactivate (I) M-Cdks....
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