Question

KARYOTYPE ANALYSIS Chromosomes in the karyotypes are arranged in groups with #1-5, #6-12, #13- 18, #19-22, X and Y. For the following six karyotypes, determine: a) the total number of chromosomes b) the sex of the individual c) the name of the chromosomal disorder d) two major symptoms of the syndrome. Note - see below for the patter...all of the attached karyotypes follow the exact same pattern. Use the syndrome sheet to identify symptoms for the chromosomal disorders that you detect. Analysis of Karyotype A (()) () Total H= 10 » 1111 X KX - Sex= Will II Jos su sesi ' • Disorder Symptoms Analysis of Karytope B • Total # . Sex= Disorder 10 » 1111 x ll X DINTI Illes or so 11 Symptoms

Answer 1

1. Analysis of karyotype A-

• Total # = 47
• Sex = male
• Disorder = Down syndrome / trisomy 21
• Symptoms = stunted growth and mental impairment

2. Analysis of karyotype B-

• Total # = 47
• Sex = female
• Disorder = Patau syndrome / trisomy 13
• Symptoms = Baby with cleft palate , mental and motor disability similar to autism, microcephaly

3. Analysis of karyotype C-

• Total # = 45
• Sex = female
• Disorder = Turner's syndrome
• Symptoms = Sterile female , Dwarfism.

4. Analysis of karyotype D-

• Total # = 47
• Sex = male
• Disorder = Jacob's syndrome / XYY syndome
• Symptoms = Learning disability , taller then average , delayed motor skill development.