If you deleted the ER N-terminal signal sequence from a gene that encodes a protein, where...
If you deleted the ER N-terminal signal sequence from a gene that encodes a protein, where would the protein end up after synthesis? (Assume no other signal sequences are present)
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The golgi |
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The smooth ER |
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The protein would be secreted from the cell |
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The cytosol |
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The lysosome |
Homework Answers
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The cytosol |
After protein synthesis in the cytosol Protein targeting takes place depending on the signal peptide on the protein. Loss of signal peptide renders protein in the cytosol itself.
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If you deleted the ER N-terminal signal sequence from a gene
that encodes a protein, where...
The ER signal sequence on a growing polypeptide chain is recognized by a signal-recognition particle (SRP)...
The ER signal sequence on a growing polypeptide chain is recognized by a signal-recognition particle (SRP) in the cytosol. What does this interaction accomplish? It cleaves the ER signal sequence from the polypeptide chain. It cleaves the ER signal sequence from the polypeptide chain. It guides the ribosome and its polypeptide to the ER. It releases the polypeptide chain from the ribosome. It speeds the synthesis of the polypeptide chain. Which of the following choices reflects the appropriate order of...
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What happens to a protein that doesn't have a signal sequence? A. It is secreted from...
What happens to a protein that doesn't have a signal sequence? A. It is secreted from the cell. B. It remains in the cytosol C. It gets degraded in the lysosome. D. It becomes a plasma membrane protein.
A protein that has an internal ER-signal sequence and a nuclear localization might end up in...
A protein that has an internal ER-signal sequence and a nuclear localization might end up in the extracellular matrix. in the cytosol. inside a lysosome. o in the plasma membrane.
A protein contains an N-terminal ER signal sequence followed by several negatively charged amino acids, an...
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Problem 4.1.3 (tags: #protein targeting, #protein topology, #transfer sequence) a) Make a map showing the location...
Problem 4.1.3 (tags: #protein targeting, #protein topology, #transfer sequence) a) Make a map showing the location of signal sequences, start transfer sequences and stop transfer sequences in protein A and protein B below that end up inserted in the membrane as shown. Protein A NH, Cytosol NA J B Scoot & Membrane Protein B COOH HAN Ν - FC ER Cisterna b) Make a map for the arrangement of signal sequences, start transfer sequences and stop transfer sequences for a...
1. Where is the ER targeting sequence located in the polypeptide chain (N-terminal, interior, or C-terminal)...
1. Where is the ER targeting sequence located in the polypeptide chain (N-terminal, interior, or C-terminal) 2. Name 4 organelles that require organelle specific targeting sequences in polypeptide 3. Name 3 final locations for proteins with ER signal sequence 4. Satranslational translocation: (a) Name the protein that the signal sequence binds to (b) Name the protein SRP binds to 5. State the function of signal peptidase 6. Name a membrane protein that is not a single pass membrane protein 7....
on the type of cell resulting in new gene e enters the nucleus and activates specifie...
on the type of cell resulting in new gene e enters the nucleus and activates specifie a step in the regulated the coat b) dynamin binds to the cytosolic e) the adaptor proteins called Sec2seSarl to relea SNAREs 14. The ed assembly of the coat found on a CoPll vesicle is surface of the donor membrane that will form the vesicle d) a Sarl-GEF in the donor membrane ca e) specitie -SNARES in the donor mem that 15. T membrane...
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3) A protein contains an N-terminal cleavable signal sequence and two further transmembrane domains. How is the protein most likely oriented with respect to the ER membrane? How is it oriented when in...
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A protein that has an internal ER-signal sequence and a nuclear localization might end up in the extracellular matrix. in the cytosol. inside a lysosome. o in the plasma membrane.
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on the type of cell resulting in new gene e enters the nucleus and activates specifie a step in the regulated the coat b) dynamin binds to the cytosolic e) the adaptor proteins called Sec2seSarl to relea SNAREs 14. The ed assembly of the coat found on a CoPll vesicle is surface of the donor membrane that will form the vesicle d) a Sarl-GEF in the donor membrane ca e) specitie -SNARES in the donor mem that 15. T membrane...
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