Question

Apoptotic cells are efficiently phagocytosed by neighboring cells or macrophages. Which one of the following does...

Apoptotic cells are efficiently phagocytosed by neighboring cells or macrophages. Which one of the following does NOT normally happen in this process?

The apoptotic cell exposes phosphatidylserine on its surface, which interacts with receptor proteins on the surface of phagocytes via "bridging" proteins.

The apoptotic cell releases some of its cytoplasmic content to induce a local inflammatory response.

The apoptotic cell loses or inactivates "don't eat me" signals.

The apoptotic cell rounds up and detaches from its neighbors, which facilitates phagocytosis

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Answer #1

The apoptotic cell loses or inactivate dont eat me signal

Note- intiatior of apoptosis are - withdrawl of growth factor and hormones which are in normal cell . But there is no signal called don eat me signal resulting in phagocytsis

Other intiators are extracellular and intracellular signal follwed by binding to marcophages via receptor and phagocytosis.

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