QUESTION: In the eve-stripe 2 enhancer, predict the effect of mutating the Kr (orange) binding sites given the preceding information (both expression graphs).
PRECEDING INFORMATION:


Answer:
QUESTION: In the eve-stripe 2 enhancer, predict the effect of mutating the Kr (orange) binding sites...
Consider cross-regulatory interactions of Drosophila gap genes
(“+” and “-“ reflect positive and negative interactions. Predict
the effect of the following conditions on gene expression domains –
specify effect on both anterior and posterior expression
boundaries.
hint: for each gap gene domain, consider anterior and
posterior boundary separately
----In the eve-stripe 2 enhancer, predict the effect of
mutating the Kr (orange) binding sites
hb 100% 90% a0 % 70% 60% 50% 40% 30% 2 % 10%EL hb gt stripe Kr...
1 & 2) Consider cross-regulatory interactions of Drosophila
gap genes (“+” and “-“ reflect positive and negative interactions.
Predict the effect of the following conditions on gene expression
domains – specify effect on both anterior and posterior
expression boundaries.
hint: for each gap gene domain, consider anterior and
posterior boundary separately
a) loss of function of (zygotic) hb on kni expression
ho 100 % 90% a0% 70% 60% 50% 40% 30 % 20% 10% EL