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When conducting current clamp recordings, as the electrode is brought closer to the surface of the...

When conducting current clamp recordings, as the electrode is brought closer to the surface of the cell, will the electrode resistance increase, decrease, or stay the same?

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Answer #1

Current clamp recordings are used to study the voltage across biological membrane. Current clamp is based on ohm law, according to this,  

V=IR

Where,

V is voltage, I is current, R is resistance

If electrode come,nearer to surface of the cell, I increases and hence R will decreased according to ohm law.

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