Question

4. Calculate the heterozygosity at a single diploid locus in a randomly mating sample of 100 individuals. Allele X is found 86 times in this population, Y is found 62 times, and Z is found 52 times. When calculating heterozygosity, do not include the correction for sample size. Remember to show your work. (3 points) 5. Answer the following questions about effective population size. (3 points) a. What evolutionary process is quantified by effective population size (N.)? b. Due to increased male variance in reproductive success within a population, there is a male specific effective population size of 210 and a female specific population size of 240 (based on estimates from autosomal genetic diversity). Using these sex specific estimates, please estimate the total population's effective population size. Don't forget to show your work. c. What is the expected time to fixation (in generations) of a new autosomal mutation entering this population (i.e., given total effective population size from part b)? Don't forget to show your work.

Answer 1

14.) Io Calculate leve heterozygosity - We have allele x = of times - y = 62 times in z = 52. Rimes Total population too Thus, x = 0.06 (frequency) Yz0.62 0.52. Afe to Hardy weinberg Equation - p2 + apq t q² =0 (6.06) " + 2pq + 0.32) ²20 0.92 + 2x0.92X0.72 + 0.72 zo 0.92 + 2x 0.6624 to 72 zo 0.92 + 1.32 + 0.72 12.967 Answer = 9.96 Se Scanned with CamScanner

* 15 Ca. Effective to is named este generatim influenced by the ocesses are generally of is a function (Ne) in a population size diverstty population effective Effective population Size (Ne) that effectively tied dhe number of indeedmals -ates in producing the next generatias Effective population she cNe). Evolutimany processes are generally info pire of population . . Genetic diversity in a popul mutation rate (M) and effective populare Effective population size ene) has an impact on population Genetics Reduction in 'Ne may be the Yesult of either population bottlenecks Effective populatias size Ne = (4 * Nm * Nf)/(Nm + Nf ) 14 x 210 x 240)/210+240) 201600 450 Ne e 440 expected time to Fixation ha 4 Na ANuth (6) i les 4 x 440 4x 440 71 1792 1792 1722 47 · 1973 - 17.9.2017 24 AN at Scanned with CamScanner : RSS