Question

Discuss the questions below with your group and write your answers and your reasoning on the board Question 1) With which definition of Gene do you agree most? Provide reasoning. • 1910- Gene as a distinct Locus • 1940 - Gene as a blueprint for a protein • 1950- Gene as a physical molecule • 1960- Gene as a transcribed code • 1970-80 - Gene as an open reading frame (ORF) • 1990-2000 - Gene as an annotated genomic entity in databases *see slides and timeline Question2) + Details 10812 1032 1083 DNA/GC Content 1084 +++++++++ ++++ +++++++++++++++ 1069 1090k 1091k 1092k 1093k 1094 1068k ++++ 1096 +++ 1096 * Monthly WS190 Gene models 792038.1 kbp-4) F5866.3a (pr-2) F5886.36 (par-2) F58B6.3a and F58B6.3b have 4 exons in common. F58B6.3a has 3 unique exons and F58B6.3b has 6 unique exons. In your opinion, are F58B6.3a and F58B6.3b two different genes or just two variations of the same gene? Question 3) 3D WS190 Gene models Y21H2B.108 Capb-1) IN THE Y7128.100 Capb-1) 471128.7.1 (doa-17) Y71128.7.2 (0-17) Y21H28.10c Cacb-1) D4- These 'genes' are all clustered within the same sequence of DNA. How many genes do you see in this image? 1, 2, 3, 4, 5?