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The following pathogen produces a capsule to protect themselves against phagocytosis by WBC a) Streptococcus pneumonia...

The following pathogen produces a capsule to protect themselves against phagocytosis by WBC

a) Streptococcus pneumonia

b) Mycobacterium tuberculosis

c)  Klebsiella pneumoniae

      d) A and C
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Answer #1

The answer is - d) A and C.

Bacteria adapt different defensive mechanisms to protect themselves against phagocytosis by WBC’s. Formation of the polysaccharide capsule is one of the defensive mechanism seen in Streptococcus pneumonia and Klebsiella pneumonia that let them escape phagocytosis by WBC. The capsule formation blocks the binding of the receptors on phagocytes with the bacterial cell wall. To be more specific the C3b (acts as an opsonin) components of the bacterial cell wall of Streptococcus pneumonia are masked by the capsule due to which the C3b receptors on the phagocytes couldn’t detect it. Whereas in Klebsiella pneumonia there are various virulence factors like the capsular polysaccharide, hypercapsule formation, lipopolysaccharide, pili which help them escaping phagocytosis.

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