Question

Window Help 2 1 10 16 + 128% - B u Tools 1.9 What is the function of the Cori cycle which involves lactate metabolism? 2. Metabolic alkalosis is prevented by removing lactate from the blood. 3. Lactate is used by the muscle for fuel. 1.10 A young woman shows symptoms of diarrhea, jaundice, dysphagia and white transverse lines (Mee's lines) on her fingernails. The doctor that was treating her diagnosed her with Arsenic poisoning. Arsenic is known to inhibit which of the following enzymes in the TCA cycle? 1. Citrate synthase 2. Succinate dehydrogenase 4. None of the above TOTAL MARKS: 20

biochemistry

Answer 1

1.9) The function of cori cycle which involves the lactate metabolism is that lactate is taken up by the liver for the synthesis of glucose.

Liver (Glucose Muscle Glucose Gluconeogenesis 6 ATP 2 Pyruvate Glucose Blood 2 ATP Glycolysis 2 Lactate 2 Pyruvate -2 Lactate -2 Lactate

1.10) The arsenic is known to inhibit the alpha ketoglutarate dehydrogenase complex in TCA cycle.