Question

15. Match each term with the best definition: Terms: 1) Lead Compound 2) Enteral Administration 3) Drug Regimen 4) Prodrug 5) Pharmacophore 6) Excipient 7) Pharmacokinetic Phase 8) Pharmodynamic Phase 9) Structure Activity Relationship 10) Bioavailability Definition: A) A structure known to be biologically active. MATCHES WITH B) A systematic approach to drug discovery. MATCHES WITH C) The minimal structure of a ligand that binds the receptor. MATCHES WITH D) A systematic plan to effect or maintain health. MATCHES WITH E) The fraction of a drug found in general circulation. MATCHES WITH F) Involves digestion by the GI tract. MATCHES WITH G) Includes excretion, distribution, metabolism and absorption. MATCHES WITH H) The effect of a drug on its biological target. MATCHES WITH 1) Pharmacologically inert substance that can be rendered biologically active. MATCHES WITH D) Pharmacologically inert substance included in drug formulation. MATCHES WITH

Answer 1

A. A structure known to be biologically active - 9. STRUCTURE ACTIVITY RELATIONSHIP

B. A systematic approach to drug discovery - 1. LEAD COMPOUND

C. The minimal structure of a ligand that binds the receptors - 5. PHARMACOPHORE

D. A systematic plan to effect or maintain health - 3. DRUG REGIMEN

E. The fraction of a drug found in general circulation - 10. BIOAVAILABILITY

F. Involves digestion by the GI tract - 2. ENTERAL ADMINISTRATION

G. Induces excretion, distribution, metabolism and absorption - 7. PHARMACOKINETICS

H. The effect of drug on its biological target - 8. PHARMACODYNAMIC PHASE

I. Pharmacologically inert substance that can be rendered biologically active - 4. PRODRUG

J. Pharmacologically inert substance included in drug formulation - 6. EXCIPIENT