Question

Could someone explain what N-linked glycosylation and O-linked glycosylation are?

Thanks!

Answer 1

a Explain what is o linle N-linked glycosylation and glycosylation are ? Answer. : N - linked glycosylation can be defined as the attachment of oligo saccharides to a nitrogen atoms , usually the N4 ez asparagine residues N- glycosylation occurs on seented of membrane and proteins, mainly in enkaryotes and archaca - most bactere ad do not carry out this modification - In enkaryotes, N-link glycosylation occurs in the lumen of endoplasmee reficulum and wedely, in archaea . - It is a complex biosyntrefie proes that regulates maturation of proteins through the secretory pathway. This cotranslational modification is regulated by a series of enzymatic reactions, which results in the pansfer of a core glycan from the lipid carrier to a protein subspate. - Its purpose is to modify a large number of proteins and can modulate the folding of substate protein thereby extending its substrate range.

0 - link glycosylation: . It can be defined as the attachment of a sugar molecule to the oxygen atom of serine of threonine residu in a profeen of glycosylation in a post-panslational modification that occurs after the profein has been synthesiza - In eukaryotes, it also occurs in ER, Golgi apparatus, and occasionally in the cytoplasm , in prokaryote, it occurs in the extoplasm . you. The N-link amino acid consensus sepnence in Asn-any AA - Ser of the The te middle amino acid can not be pretine. (Pro). Most o- link carbohydrate covalent attachments. to proteins involved a linkage behween the mono sacchared N- acetygalacto samise and the amino acids sesine or threonine.
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