Question

Match the following pathogens with their method of entry into a host cell. Salmonella species Mycobacterium tuberculosis Staphylococcus aureus Shigella species Yersinia pestis Match each of the options above to the items below. Entry through a wound. Entry through an insect bite. Entry through intestinal M cells. Entry through induced endocytosis. Entry through directed macrophage uptake.

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Answer 1

1. Salmonella species - Entry through induced endocytosis

    Salmonella invade host cells by caveolae-dependent endocytosis

2. Mycobacterium tuberculosis - Entry through directed macrophage uptake

Alveolar Macrophages, the first line of defence in lungs ingest M. tuberculosis, when its inhalation through aerosols.

3. Staphylococcus aureus - Enter through a wound

S. aureus can enters through direct contact with open wound or cut on the skin

4. Shigella species - Entry through intestinal M cells

Shigella ingested through oral route invades colonic epithelial cells through M cells in the intestine.

5. Yersinia pestis - Enter through an insect bite

Y. pestis transmitted to the humans through infected vector fleas.