Question

7) Briefly differentiate the key features of A-, B-, and Z-form DNA, including “handedness”, syn/anti nucleotide conformations, and sugar puckets.

Answer 1

	A-DNA	B-DNA	Z-DNA
Handedness	Right handed	Right handed	Left handed
Syn/anti nucleotide conformations	Anti conformation	Anti conformation	Anti at C Syn at G
Sugar puckets	C3’ -endo	C2’- endo	C: C2’- endo G: C2’- exo
Rise per base pair	2.3 Å	3.32 Å	3.8 Å
Base pairs per turn of helix	~11	~10	12
Base pairs per helix repeat	1	1	2