Question

The same transporters we discussed on Wednesday that are part of the shark renal gland/chloride cells are involved in osmoregulation in the loop of Henle. Based on what you know about these transporters and what is happening in the loop of Henle, you would expect to find the of the epithelial cells lining the of the loop of Henle OA. NKCC channel on the basal side; descending limb OB. Cl- channel on the apical side; thick ascending limb OC. Cl- channel on the basal side; descending limb OD. NKCC channel on the apical side; thick ascending limb OE. NKCC channel on the apical side; descending limb

Answer 1

We would expect to find the NKCC channel on the epical side of the epithelial cells lining the thick ascending limb of the loop of Henle.

Na-K-Cl cotransporter resides at the epical surface of the epithelial cells of thick ascending limb of loop of Henle to collect excess Na+, K+, Cl- ions in the epithelial cells for osmoreguation.