Question

You wish to create a transgenic mouse that is completely hairless. You introduce the appropriate mutation into embryonic stem cells and implant those cells into early embryos. Those embryos are placed in a surrogate mouse who then gives birth to the first generation of mice. These mice are further bred. Which of the following is(are) true? First generation is completely hairless Second generation is completely hairless Third generation is completely hairless Second generation is heterozygous Second generation are crossed with each other First generation are crossed with each other

Answer 1

Ans- first generation does not produce any hairless mouse. when first-generation heterozygous crossed with each other produce hairless mouse in the second generation but not all mice are hairless in the second generation. the second generation also produces normal homozygous, heterozygous, and homozygous knockout (hairless mouse) mouse.

so option first generation are crossed with each other is the correct option.
sexagente ceilal type farent Iweragente motere (chimeric mouse ++ +- Heterozygous Nosmal Heterozygous 12 generation (0) 2 beh + + +/- Normal Heterozy you Hetereoty gory Homory yous Bioeth of knockout mouse Cheur luss mouse