Homework Answers
From the diagram, it is clear that mice injected with leptin have a lower resulting body mass as compared to the control group that is injected with saline.
Leptin is a hormone that acts on the brain and plays a major role in the energy expenditure of the body. When the leptin levels are high in the bloodstream, the brain signals the body to indulge in energy-expensive activities and promotes higher metabolism. This leads to weight loss.
Observation:
In the first group of mice, that have defective genes and were leptin deficit, showed almost 50% decrease in body mass compared to the control.
Whereas, the second group of mice with functional genes showed a lower percentage of decrease in body mass when compared to the first group.
Therefore, we can conclude that leptin injections are successful in promoting weight loss in mice, and they are more efficient when the mice have defective leptin-producing obese genes.
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