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1. What is the ER/PR and HER2 expression profile of tumors that might benefit from PIQRAY treatment?
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IF THE BREAST CANCER CELLS HAVE ESTROGEN RECEPTORS THE CANCER IS CALLED ER POSITIVE BREAST CNCER .IF THE BREAST CANCER CELLS HAVE PROGESTERONE RECEPTORS ,THE CANCER IS CALLED PR POSITIVE BREAST CANCER. IF THE CELLS DONOT HAVE EITHER OF THESE 2 RECEPTORS THE CANCER IS CALLED ER /PR NEGATIVE

HER2 POSITIVE CANCER IS THE CANCER THAT TESTS POSITIVE FOR A PROTEIN CALLED HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 WHICH PROMOTES GROWTH OF CANCER CELLS . IN ABOUT 1 OF EVERY FIVE BREAST CANCER CELLS HAVE A GENE MUTATION THAT MAKES AN EXCESS OF HER2 PROTEIN

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