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how does conceptualization and operationalozation of constructs help write good research questions

how does conceptualization and operationalozation of constructs help write good research questions
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For any good research proposal two components are most important which is conceptualization and operationalization. The primary component is getting an idea or concept for answering certain research question to solve the problem. This concept is very important to properly address the problem, but operationlization is equally important for the execution of the research problem with the help of well defined material and proper methodology.

Suppose if I got an idea/concept to cure a disease using nutraceuticals on the basis of previous knowledge (this would be a part of conceptualization) but it can not be concluded without its further validation through potent experimental prcedures using in vitro and in vivo animal models (operationalization) and it would be very crucial for a product development or other innovative things like copyright or patent.

The pathways is

Cocenptualization (concept)-------> Operationalization (Execution of work plan)-------> Product development

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