Homework Answers
- Steroid hormones such as estrogen, progesterone and testosterone use intracellular receptor for transmitting their signals. Steroid hormones have target inside the cell so that they need intracellular receptors.
- Steroid hormones are hydrophobic as well as small molecules easily pass the cell membrane and bind to the intracellular receptors. Due to the binding of hormones leads to confirmational changes to the receptor and activate transcriptional factors. Then the supression of gene expression is done by activated hormone receptor complex.
Add Answer to:
5. Name an example of extracellular signal that does NOT have an extracellular receptor.
What does a target cell require to respond to an extracellular signal molecule? Choose ONE OR...
What does a target cell require to respond to an extracellular
signal molecule?
Choose ONE OR MORE:
appropriate intracellular signaling pathways
a receptor that recognizes the signal molecule
access to the signal molecule
the appropriate machinery to produce and secrete the signal
molecule
effector molecules that alter cell behavior in response to the
signal molecule
What is the key activating signal in the TNF receptor signaling pathway that occurs downstream of...
What is the key activating signal in the TNF receptor signaling pathway that occurs downstream of TNF-alpha binding to the extracellular domain? What are the analogous activating signals downstream of receptor activation in the GPCR and RTK pathways.
What is the key activating signal in the TNF receptor signaling pathway that occurs downstream of...
What is the key activating signal in the TNF receptor signaling pathway that occurs downstream of TNF-alpha binding to the extracellular domain? What are the analogous activating signals downstream of receptor activation in the GPCR and RTK pathways.
Drosopholia eye development is an example of cell differentiation directed by signal binding to a receptor...
Drosopholia eye development is an example of cell differentiation directed by signal binding to a receptor tyrosine kinase (RTK). In this pathway, R7 photoreceptor development requires a receptor (SEV, sevenless), which is activated by binding to a plasma membrane bound signal (BOSS, bride-of-sevenless) displayed on the adjacent R8 cell Receptor activation leads to activation of RAS via two proteins, Drk (down- stream of receptor kinases) and Sos (son-of-sevenless). Activated RAS leads to activation of a phosphorylation cascade that activates the...
The ability of a single signal molecule to bind to a receptor and trigger several signal...
The ability of a single signal molecule to bind to a receptor and trigger several signal transduction pathways simultaneously: a. Is common to all plasma membrane receptor proteins b. Does not occur in animals c. Is a key feature of the receptor tyrosine-kinase system d. Uses a diacylglycerol-mediated pathway
Many extracellular proteins are internalized by receptor-mediated endocytosis. What are the molecular signals that trigger uptake...
Many extracellular proteins are internalized by receptor-mediated endocytosis. What are the molecular signals that trigger uptake of a protein by receptor mediated endocytosis?
What mechanisms have we encountered that ensure that a signal initiated by a growth factor receptor...
What mechanisms have we encountered that ensure that a signal initiated by a growth factor receptor can be greatly amplified as the signal is transduced down a signaling cascade in the cytoplasm? Conversely, what signaling cascade(s) strongly limit the possible amplification of a signal initiated at the cell surface?
Select one compound (drug or toxicant) that targets one of the three receptor types(G-protein coupled receptor pathway, A receptor tyrosine kinase pathway, An ion channel pathway ) and discuss the fol...
Select one compound (drug or toxicant) that targets one of the three receptor types(G-protein coupled receptor pathway, A receptor tyrosine kinase pathway, An ion channel pathway ) and discuss the following for the selected compound: The name of the receptor involved The type of ligand that the drug or toxicant presents: Agonist, antagonist Are there natural ligands that interact with the receptor? If so explain the interaction. Provide a brief explanation of the mechanism of the cellular response upon ligand...
You want to tag the extracellular part of a single-pass transmembrane receptor with GFP, which re...
You want to tag the extracellular part of a single-pass transmembrane receptor with GFP, which requires that you modify the DNA sequence encoding the receptor to also include the DNA sequence encoding GFP. a) Would you tag the receptor so that GFP is fused to that portion of the polypeptide that is translocated into the ER lumen during translation? Or instead, would GFP be fused to that portion of the polypeptide that remains in the cytosol during translation? (2 points)...
A chemical signal can have different effects in different tissues, depending on the receptor type to...
A chemical signal can have different effects in different tissues, depending on the receptor type to which autonomic neurotransmitters and hormones bind to. For this reason, it is important to specify the signal molecule and its receptor and subtype when describing the control of a tissue. Most smooth muscle neurotransmitters and hormones bind to G-protein linked receptors. The second messenger pathways then determine the muscle response: IP3 triggers contraction and cAMP promotes relaxation. What neurotransmitter and its GPCR triggers IP3...
What does a target cell require to respond to an extracellular
signal molecule?
Choose ONE OR MORE:
appropriate intracellular signaling pathways
a receptor that recognizes the signal molecule
access to the signal molecule
the appropriate machinery to produce and secrete the signal
molecule
effector molecules that alter cell behavior in response to the
signal molecule
Drosopholia eye development is an example of cell differentiation directed by signal binding to a receptor tyrosine kinase (RTK). In this pathway, R7 photoreceptor development requires a receptor (SEV, sevenless), which is activated by binding to a plasma membrane bound signal (BOSS, bride-of-sevenless) displayed on the adjacent R8 cell Receptor activation leads to activation of RAS via two proteins, Drk (down- stream of receptor kinases) and Sos (son-of-sevenless). Activated RAS leads to activation of a phosphorylation cascade that activates the...
Most questions answered within 3 hours.
-
Where is the error in this code sequence?
String s1 = "Hello";
String s2 = "ello";...
asked 11 months ago -
Financial data for Joel de Paris, Inc., for last year
follow:
Joel de Paris, Inc.
Balance...
asked 11 months ago -
Consider this reaction:
Al2(SO4)3 (aq)+ BaCl3
(aq) Al2Cl6 (aq)- +
3BaSO4(s) . What is the...
asked 11 months ago -
Suppose that Savneet is considering increasing her
recent random sample from 20 car rentals to 40...
asked 11 months ago -
Trucks arrive at an unloading terminal at an average rate of 120
per hour.
Trucks arrive...
asked 11 months ago -
Why are methanol and ethanol completely soluble in water while
octanol is not very little soluble....
asked 11 months ago -
A facilities manager at a university reads in a research report
that the mean amount of...
asked 11 months ago -
When the CuSO4 is rehydrated by adding water to the anhydrous
compound, is this an endothermic...
asked 11 months ago -
A ray of sunlight is passing from diamond into crown glass; the
angle of incidence is...
asked 11 months ago -
A block of mass 0.249 kg is placed on top of a light, vertical
spring of...
asked 11 months ago -
how do the kidneys compensate in the presences of acidosis
a) trigger hyperventilate
b) reserve acid...
asked 11 months ago -
Question 501 pts
The rental rate of capital to the firm increases. Which of the
following...
asked 11 months ago