Question

For the following six questions, answer using the single best description of the following five options a.-e. You may use each option as often as you wish, including multiple times or not at all, but each question has ONE answer. Reversible inhibitors b. Irreversible inhibitors c. Uncompetitive inhibitors d. Competitive inhibitors Non-competitive (allosteric) inhibitors inhibitors have structural similarity to substrates, intermediates, or products of the reaction catalyzed by the target enzyme blocking the active site of the enzyme. inhibitors form covalent bonds with the target enzyme. inhibitors bind to protein part that is different from active site and may not show substrate/product similarity. inhibitors bind to the target enzyme and substrate forming a complex that prevents catalysis. inhibitors form non-covalent interaction with the target enzyme and are preferable as drugs. For the following three questions, answer using the single best deseription of the following five options a.-c. a. DNA replication b. Protein synthesis c. Cell wall biosynthesis b-lactams inhibit Quinolones inhibit Tetracyclines inhibit is/are typically bacteriostatic. Tetracycline. Penicillins. Vancomycin Ciprofloxacin ("Cipro"). Both (A.) and (D.) above are correct is/are typically bactericidal. a. Tetracycline. b. Penicillins. Vancomycin. Ciprofloxacin ("Cipro"). Both (C.) and (D.) above are correct. (B). (C), and (D) above are corect d.

Answer 1

1) d- competitive inhibitors

2) b- irreversible inhibitors

3) e- non competitive inhibitors

4) c- uncompetitive inhibitors

5) a- reversible inhibitors

6) c- cell wall biosynthesis

7) a- DNA replication

8) b- Protein synthesis

9- Both A and D (e)

10- B,C, D (f)