Briefly describe the function of clathrin cell membranes and their role in LDL uptake from
blood.
Ans) Clathrins are coat proteins which bind to the sorting signal of vesicles carrying the cargo protein and transferred it to the signal receptor. The signal sequence of LDL is Asn-Pro-X-Tyr (NPXY) here X represents any amino acid and this vesicle is transported to LDL receptor present in plasma membrane via Clathrin proteins.
LDL receptor bind to apoB protein and then the vesicles are pinched off by dynamin proteins followed by vesicle uncoating.The uncoated vesicle will fuse with endosome and thus release apoB protein which gets broken down by the hydrolytic enzymes present in the lysosome.
Briefly describe the function of clathrin cell membranes and their role in LDL uptake from blood.
7) Briefly describe the function of LDL and HDL in the body and explain why one is known as the "good" cholesterol and the other as the "bad" cholesterol
7) Briefly describe the function of LDL and HDL in the body and explain why one is known as the "good" cholesterol and the other as the "bad" cholesterol
The electrochemical potential that is found across cell membranes can play a role in what types of processes? Choose all that apply the movement of a muscle the uptake of molecules against a concentration gradient the transmission of a nervous system signal the exchange of gases between capillaries and surrounding cells
Briefly describe O2 transfer from the atmosphere into the mitochondria of an insect cell. Name four variables that if altered would result in a decrease in rate of O2 uptake by the cell. Include the direction of change for the variable (increase or decrease) along with a brief explanation that references Fick’s Law of Diffusion where appropriate.
briefly describe some methods of reducing the effects of an internal uptake of radioactivity
The role of very low density lipoproteins is 1. Scavenging the cholesterol from cell membranes 2. Transporting of lipids from liver to tissues 3. Transporting of cholesterol esters to the liver 4. Both A and B are correct 5. All of the above are correct
6. Briefly describe the pulmonary circulation. 7. Briefly describe the systemic circulation. 8a. What is the function of the platelets? 8b. What is the function of red blood cells? 9a. Name 2 different functions of white blood cells? 9b. What is the most common white blood cell? 10a. What is leukemia? 10b. What is hemophilia?
Mention three pathways to the uptake of Renewable Energy Sources in Transportation (RES-T), and briefly describe them.
write a paragraph to describe the white blood cell and red blood cell morphology from monocytosis slide (blood smear slide)?
Assignments, Chapter 38, Agents to Control Blood Glucose Levels Briefly describe the pathophysiology of diabetes mellitus including alterations in metabolic pathways and changes to basement membranes.
Drugs affect the cell function in a variety of ways. Briefly describe and provide an example of an agonist, a competitive antagonist, and a noncompetive antagonist.