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F. The first heart sound (lub) is heard when the AV valves/SL valves (circle one) Close/Open (circle one).
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Both lub and dub sounds are produced only when the AV valves and SL valves close respectively. When AV valves are closed to prevent the black flow of blood from ventricle to atrium first heart sound lub is produced.

So answer is AV valve and close.

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