Discuss how bacterial cells might resist phage infections. In your response explain the mechanisms involved and...
Discuss how bacterial cells might resist phage infections. In your response explain the mechanisms involved and speculate on the possible strategies of resistance. (15)
Homework Answers
Answer - Bacteria have a adaptive immunity system which can defend themselves against infection by bacteriophages. This adaptive immune system is called CRISPR-Cas. This immune system is present in some bacterias . This immune system (CRISPR-Cas) works by incorporating small pieces of DNA taken from the infecting phage on the so-called CRISPR-locus which is a specific position on the bacterial genome . This sequence is recognised by CRISPR-Cas by the phage which carry the same sequence and destroyed and thus this ensures that the bacterium now is immune to that phage through its CRISPR-Cas system. This is how phages deal with CRISPR-Cas is highly valuable to develop and optimise phage therapies.
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Discuss how bacterial cells might resist phage infections. In
your response explain the mechanisms involved and...
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