Question

Inheritance of a recessive disorder Assume that a recessive allele (f) is associated with a severe language disorder. An unaffected male wants to determine the genotypes of his wife, his parents, and himself. His mother has the language disorder. Neither he nor his wife has the language disorder, but one of their five children does. What is the genotype for each individual? Answers may be used more than once or not at all.

Answer 1

Inheritance of a recessive disorder Assume that a recessive allele (h) is associated with a severe language disorder. An unaffected male wants to determine the genotypes of his wife, his parents, and himself. His mother has the language disorder. Neither he nor his wife has the language disorder, but one of their five children does. What is the genotype for each individual? Answers may be used more than once or not at all. (Note: the gene associated with this language disorder is on an autosome.) Answer Mother ff Father Either FF or F Wife F Himself Ff Given that the mother of the male is atfected. Means, he nherited one defective allle from his mother, thus the male is a carrier The male and his wife together had an affected child, means the wife is also a carrier but not affected. Assume that the gene F codes for nomal allele and the gene f cdes for defective allele. Cross between two carriers will have the offspring with the following genotypes. Ff* FfFF 14), Ff (1/2), ff (1/4).