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Explain the concept of rational chemotherapy and give an example of how it is applied in...

Explain the concept of rational chemotherapy and give an example of how it is applied in treatment of parasitic diseases.

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Answer #1

Rational Chemotherapy includes a combination of drugs.

This is given with a idea that if parasite developes resistance to a drug , other can successfully eliminate it. Further with use of a single drug developement of resistance is fastly developed.

Take example of malarial parasite:

Use of combination drugs like Primaquine , Chloroquine and quinine - clindamycin.

ACT based therapy like Artemether piperaquine

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