Question

treatment with high salt would release which protein or proteins from the bilayer?

Box Smartwork 03/06/20 70% 1st attempt See Hint To study the structure of a particular membrane protein, the target protein is usually removed from the membrane and separated from other membrane proteins. Shown below are three different proteins associated with the cell membrane. Treatment with high salt would release which protein or proteins from the bilayer? Choose one or more wowo 14 OF 17 OUESTIONS COMPLETED < 09/17 > De 9

Answer 1

Protein in option C can be released from lipid bilayer by treating with high salt.This is because it is a peripheral protein and does not extend into the hydrophobic interior of the lipid bilayer at all. Instead it is bound to face of the membrane by non-covalent interactions with other membrane protein.High salt will not affect the lipid bilayer, but disrupt the protein-protein interaction releasing the peripheral protein.

Protein in option A cannot be released because it is embedded in the lipid bilayer. High salt does not affect lipid bilayer.

Protein in option B cannot be released because it bound to the plasma membrane by a GPI anchor and can be released by the use of an enzyme called phosphatidylinositol-specific phospholipase C.

Option D is wrong because protein in option C can be released by high salt.