Question

Which of the following mutagens requires replication to alter DNA? MMS (an alkylating agent) X-Ray 5-bromouracil...

Which of the following mutagens requires replication to alter DNA?

MMS (an alkylating agent)

X-Ray

5-bromouracil

Nitrous acid (a deaminating agent)

UV light

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Answer #1

MMS alkylates bases in the DNA and Nitrous acid deaminates, deamination of cytosine produces uracil, UV light produce pyrimidine dimers, X-rays can break DNA and 5-Bromouracil is inserted into DNA during replication so the mutagen which requires replication to alter DNA is 5-Bromouracil.

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