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Identify four broad categories of toxins' mode of action.

Identify four broad categories of toxins' mode of action.

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Answer #1

Modes of action :

1- Uncouplers : These uncouple the oxidative phosphorylation , that is the electron transfer and ATP production.

2- AchE inhibhition : AchE is an enzyme which breaks down the Ach and regulates the tranmission in normal impulses. Inhibhition of AchE leads to unregulation nerve signal transmission.

3- CNS seizure agents : They act by acting as antagonist at the receptor , thus prevenring the biological response.

4- Irritants : They cause inflammation of the living cell line. This results in increased cell size and volume.

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