Question

Lipoamide is a coenzyme prosthetic group for several enzymes, including the pyruvate dehydrogenase complex. In the pyruvate dehydrogenase reaction the prosthetic group cycles through three distinct structural forms: the oxidized form, the reduced form, and the reduced form with an acetyl group bound. Modify the three partial structures below to represent these three structural forms. R–NH represents a lysine amino residue of the dihydrolipoyl transacetylase subunit of pyruvate dehydrogenase, to which the lipoamide is attached.

R-NH R-NH R-NH If you need to reset the drawing, click on the "remove changes" button (looks like two red arrows) in the Tools menu of the drawing module.

Answer 1