As per Hardy-Weinberg Equilibrium, let
p = Frequency of Dominant Allele
q = Frequency of Recessive Allele
Also p + q = 1
Now,
p2 = Frequency of Homozygous Dominant Genotype
2pq = Frequency of Heterozygous Dominant Genotype
q2 = Frequency of Homozygous Recessive Genotype
Here genotypic numbers of this population:
Number of Homozygous Dominant Genotype = p2 = 60
Number of Heterozygous Dominant Genotype = 2pq = 140
Number of Homozygous Recessive Genotype = q2 = 800
Genotypic frequency of Homozygous Dominant Genotype AA = Number /
Total = 60/1000 = 0.06
Genotypic frequency of Dominant Genotype Aa = Number / Total =
140/1000 = 0.14
Genotypic frequency of Recessive Genotype aa = Number / Total =
800/1000 = 0.80
Allelic number (A) for Homozygous Dominant Genotype AA = AA
Number*2 = 60*2 = 120
Allelic number (A) for Dominant Genotype Aa = Aa Number*1 =
140
Allelic number (A) for Recessive Genotype aa = aa Number*0 = 0
=
Total (A) = 260
Allelic number (a) for Homozygous Dominant Genotype AA = AA
Number*0 = 0
Allelic number (a) for Dominant Genotype Aa = Aa Number*1 =
140
Allelic number (a) for Recessive Genotype aa = aa Number*2 = 800*2
= 1600
Total (a) = 1740
Allelic frequency of A = Total (A) / Total = 260/2000 =
0.13
Allelic frequency of a = Total (a) / Total = 1740/2000 = 0.87
Expected genotypic frequencies for next generation =
Genotypic frequency of AA = Allelic frequency of A * Allelic
frequency of A = 0.13 * 0.13 = 0.0169
Genotypic frequency of Aa = 2 * Allelic frequency of A * Allelic
frequency of a = 2 * 0.13 * 0.87 = 0.2262
Genotypic frequency of aa = Allelic frequency of a * Allelic
frequency of a = 0.87 * 0.87 = 0.7569
Expected genotypic numbers for next generation (Assuming population
of 10,000):
Genotypic Number of AA = Genotypic frequency of AA * 10000 = 0.0169
* 10000 = 169
Genotypic Number of Aa = Genotypic frequency of Aa * 10000 = 0.2262
* 10000 = 2262
Genotypic Number of aa = Genotypic frequency of aa * 10000 = 0.7569
* 10000 = 7569
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