Question

1st attempt Which of the following features would increase the chances of foreign DNA being stably maintained by a recipient cell? Choose one or more: A. The DNA is circular and capable of self-replication. B. A portion of the DNA shares 100% identity with a spacer in the cell's CRISPR region C. It shares extensive homology with one or more host genes. D. Its methylation pattern differs from the host DNA. E. The foreign DNA has insertion sequences (elements). v 0

Answer 1

The foreign DNA should have homology to host DNA, so that it can integrate with host DNA and it will increase its stability. A circular and self replicating molecule is more stable than a non replicating molecule, as it can maintain itsself inside the host cell. If a foreign DNA contains insertion sequences, it can insert into the host DNA that will also increase its stability in the host cell.

Hence, options A, C, and E are correct.