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6. Jasmine is a woman who is effected with a disease caused by a mutation in...

6. Jasmine is a woman who is effected with a disease caused by a mutation in an imprinted gene that is paternally-expressed (maternally silenced).

Jasmine and her male partner are considering having a child. Imagine you are a genetic counseler. Do you tell them they should worry about their child having the disease or not? Why? (2points)

Jasmine’s father is considering having a child with her new female partner (not Anurak’s mother). Imagine you are a genetic counseler. Do you tell them they should worry about their child having the disease or not? Why? (2points)

Jasmine remembers hearing that one of her parents’ grandfathers had the same disease, but he can’t remember which parent. Do you think it was his mother’s grandmother or his father’s grandmother? (1points)

Is it surprising that Jasmine has the disease, given that she is a female? Why? (2points)

         

7. Consider the problem below. Cage 1 contains organisms caught in the wild. Other cages represent the results of a cross between the two parents indicated at the top of the cage.

Which trait is dominant? (2points)
Which cage made you confident of your answer above? (2points) What are the genotypes of the parents in each cage? (2points)

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Answer #1

There is no reason to be worried because the gene is paternally expressed.

Jasmine has the gene but when she give one gamete to form zygote the mutated gene will not be expressed as it is maternal as jasmine is giving the gene. And his partner has no mutation.

So there is nothing to be worried .

The parent will be his father grandfather that why jasmine is effected because his grand grandfather gives the gene to grandfather who gives to his father and his father gives to jasmine.

Ii is not maternal because if maternal then when jasmine mother had the gene , jasmine would not be affected as it is paternally expressed.

Thank you

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